Bruno L. Victor, PhD

Principal Investigator of the Laboratory

Bruno L. Victor is currently an assistant researcher at BioISI research center and Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa (FCUL). He got his degree in Biochemistry from the Faculdade de Ciências e Tecnologia da Universidade de Coimbra and his PhD in Biochemistry from Instituto de Tecnologia Química e Biológica (ITQB), Universidade Nova de Lisboa (UNL). After performing an initial Post-Doc also at ITQB-UNL, he then moved to BSIM therapeutics, as a research scientist. He was then awarded with two Post-Doc fellowships at FCUL and Faculdade de Farmácia da Universidade de Lisboa (FFUL), until he returned to FCUL to its current position. His major scientific interests are focused on the development and application of new computational approaches in the identification of new therapeutics against several diseases.

 

Israa Alakhras Ijnadi, MSc

PhD student

Israa Alakhras Aljnadi, got her bachelor’s degree in
Pharmacy from Syrian Private University (SPU). In 2020, she finished her master’s degree in Biopharmaceutical sciences in the Faculty of Pharmacy at the University of Lisbon and started her Ph.D in pharmaceutical chemistry and therapeutics in 2021. Her work focuses on designing selective and promising inhibitors of G4-DNA and helicase
interaction in breast cancer. Collaboration with Alexandra Paulo (FFUL/imed).

 

 

Bruno Calçada, MSc

PhD student

Bruno Calçada is a PhD student in Theoretical Biochemistry from Faculty of Sciences, University of Lisbon (FCUL) since 2021. He got his Master and Bachelor degrees in Chemistry and Biochemistry in 2014 and 2012, respectively, at FCUL. In 2015 he joined the phytopharmaceutical company ASCENZA – A ROVENSA company – as a Quantitative Struture-Activity Relationship (QSAR) technician to perform QSAR assessments, which support the company’s registrations worldwide. Nowadays, he works as a toxicologist and his major scientific interest is the use of new approach methodologies in the application of the 3Rs principles (reduce, refine and replace). Currently, he is developing his PhD thesis focused on the development of in silico methods to support decision-making for chemical risk assessment applied to endocrine disruptors. Collaboration with Paulo J. Costa (Computational Chemistry Molecular Interactions laboratory) and Andrea Sartini (Lhasa Limited).

 

Marta Batista, MsC

PhD Student

Marta Batista is a Master’s degree student in Bioinformatics and Computational Biology from FCUL since 2020. She got her Bachelor’s degree in Biochemistry in 2020 from the Faculty of Sciences, University of Lisbon (FCUL). Currently, she is developing her Master’s thesis project focused on the discovery of a new hybrid therapeutic agent against malaria by targeting the Aquaglyceroporin from plasmodium spp. using computationally-based methodologies. Collaboration with Paulo J. Costa (Computational Chemistry Molecular Interactions laboratory @ FCUL)

 

 

Tiago Dias, BSc

MSc Thesis Student

Since 2020, Tiago Dias is a Master’s student in Biochemistry from FCUL. In 2019 he got his Bachelor’s degree in Bioinformatics in Escola Superior de Tecnologias do Barreiro (Polytechnic Institute of Setúbal), and currently, he is developing his Master’s thesis project focused on studying and developing new computational approaches to identify and characterize halogen bonds and on the development of innovative approaches of computing them in silico, using computational simulations. Collaboration with Paulo J. Costa (Computational Chemistry Molecular Interactions laboratory @ FCUL).

 

 

Bárbara Almeida, BSc

MSc Thesis Student

Bárbara Almeida is a Master’s degree student in Bioorganic Chemistry from FCT Nova since 2021. In 2021, she got her Bachelor’s degree in Chemistry at FCUL, and currently, she is developing her Master’s thesis project focused on the structural characterization and identification of novel inhibitors ofrespiratory proteins from human bacterial pathogens using multiple computational approaches. Collaboration with Manuela Pereira (Bioenergetics Lab @ FCUL).

 

 

 

Beatriz Farinha, BSc

MSc Thesis Student

Since 2021, Beatriz Farinha is a Master´s degree student in Biopharmaceutical Sciences from FFUL. She got her Bachelor´s degree in Biochemistry in 2020 from the Faculty of Sciences, University of Lisbon (FCUL) and she is currently developing her Master’s thesis project focused on identifying novel TGR5 agonist(s) and inquiring about this protein’s role in adipose exosome pathways in NAFLD, by combining multiple computational and experimental methodologies. In collaboration with Rui Castro (Liver Disease Diagnosis and Therapeutics @ FFUL/imed)

 

 

Rita Emídio, BSc

MSc Thesis Student

Rita Emídio is a Master’s degree student in Medicinal and Biopharmaceutical Chemistry from FFUL. She got her Bachelor’s degree in Chemistry in 2021 from the Faculty of Sciences, University of Lisbon (FCUL). Currently, she is developing her Master’s thesis project focused on the optimization of indoloisoquinoline derivatives as new anticancer therapeutics using multiple experimental and computational approaches. Collaboration with Alexandra Paulo (FFUL/imed).

 

 

Rita Guerra, BSc

MSc Thesis Student

Since 2021, Rita Guerra is a Master’s degree student in Bioinformatics and Computacional Biology from FCUL. She got her Bachelor’s degree in Biochemistry in 2021 from the Faculty of Sciences, University of Lisbon (FCUL). Currently, she is developing her Master’s thesis project focused on the study and identification of a possible dependency of anti-tumor TKI drug’s efficiency with the TME acidity using computational-based methodologies. In collaboration with Miguel Machuqueiro (Molecular Modeling and Simulation laboratory @ FCUL)

 

 

 

Vasco Neto, BSc

MSc Thesis Student

Vasco is a Master’s degree student in Biochemistry from FCUL since 2021. He got his Bachelor’s degree in Biochemistry in 2021 from the Faculty of Sciences, University of Lisbon (FCUL), and currently, he is developing his Master’s thesis project focused on the computational design and probing of small molecules and peptides towards inhibition of HbS aggregation. In collaboration with Nuno Galamba (FCUL).